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Commercial products may vary in: Total milligrams per vial Tesamorelin-to-ipamorelin mass ratio Free base versus acetate content Excipients and stabilizers Actual net peptide content Sterility, endotoxin, and aggregate controls Equal milligrams do not mean equal molar exposure: Tesamorelin has a free-base molecular weight of approximately 5,135.9 Da, while ipamorelin is approximately 711.9 Da

Hollande et al., 2019

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Enhanced autophagy, the cellular process by which damaged or misfolded proteins are identified and cleared, was observed, suggesting improved capacity to remove the amyloid and tau aggregates that accumulate in neurodegeneration